Cardiac Natriuretic Peptides
نویسندگان
چکیده
منابع مشابه
Cardiac natriuretic peptides for cardiac health.
The cardiac natriuretic peptides, ANP (atrial natriuretic peptide) and BNP (brain natriuretic peptide), are secreted by the heart in proportion to cardiac transmural pressures. They possess a wide range of effects in multiple tissues facilitating overall pressure/volume homoeostasis. The close relationship between plasma concentrations of these peptides and 'cardiac load' has led to their use a...
متن کاملNatriuretic peptides in cardiac and renal failure
linkage essential for receptor binding. ANP and BNP are cardiac hormones mainly secreted from the atrium and the ventricle respectively, whereas CNP is of endothelial origin. ANP and BNP bind to the natriuretic peptide A-receptor (NPR-A) and mediate the biological actions of natriuresis, vasodilatation and renin inhibition. In contrast, CNP lacks renal actions but causes vasodilatation via bind...
متن کاملCardiac Natriuretic Peptides, Hypertension and Cardiovascular Risk
Prevalence of cardiovascular (CV) disease is increasing worldwide. One of the most important risk factors for CV disease is hypertension that is very often related to obesity and metabolic syndrome. The search for key mechanisms, linking high blood pressure (BP), glucose and lipid dysmetabolism together with higher CV risk and mortality, is attracting increasing attention. Cardiac natriuretic p...
متن کاملBrain Natriuretic Peptides and Calcitonin Gene-Related Peptide in Diagnosis of Cardiac Involvement in Major Thalassemia Patients
Background: Cardiac dysfunction is one of the major causes of morbidity and mortality in thalassemia patients. This study aimed to compare the effect of Brain Natriuretic Peptides (BNP) and Calcitonin Gene-Related Peptide (CGRP) with echocardiographic findings in early diagnosis of cardiac disease in major thalassemia patients. Materials and Methods: This study was performed on 80 patients amo...
متن کاملNatriuretic Peptides
Renal dysfunction has emerged as an important independent predictor of adverse outcomes, renal as well as cardiovascular. Renal function is crucially affected by intrinsic renal factors (particularly remaining functional renal mass), hemodynamic function (renal perfusion pressure, renal venous pressure), oxygen delivery, and neurohumoral input. The natriuretic peptides play an important role in...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2009
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2009.05.044